Results
Baseline characteristics of AECOPD patients.
In this cross-sectional study, a total of 598 AECOPD patients were enrolled. In the end, the LHS of 111 patients (26%) were <7 days (Normal LHS, N-LHS), 218 patients (51%) were 7-10 days (Mild Prolonged LHS, MP-LHS), and 100 patients (23%) were≥11 days (Severe Prolonged LHS, SP-LHS) (Figure 1). The demographic data of the patients were presented in Table 1. The significant differences in age and the rates of CAP, CCP, and hypertension were observed among 3 groups.
Clinical presentations and laboratory data of AECOPD patients.
As shown in Table 2, white blood cells (WBC), neutrophils (NS), NS%, lymphocytes%, erythrocyte sedimentation rate (ESR), PH, and albumin (ALB) were significantly different among the 3 groups.
Multiple logistic regression analysis in AECOPD patients.
To explore independent factors associated with LHS in AECOPD patients, multiple logistics regression was performed. Since significant collinearities among WBC, NS, and NS% were observed, WBC and NS% were excluded. In the multiple logistics regression model, 9 factors in significant association with LHS in univariate analysis, including age, the rates of CAP, CCP, and hypertension, NS, lymphocytes%, ESR, PH, and ALB were included. Subsequently, our data identified that the rates of hypertension and CCP were independently associated with LHS in AECOPD patients (Table 3).